Biotin and derivatives
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | 98.0% | 884.92 | C38H64N2O21 | 100 MG
Bis-PEG13-NHS ester is a polyethylene glycol (PEG)-based NHS ester linker supplied for research use in bioconjugation, antibody-drug conjugate (ADC) synthesis, and PROTAC linker construction. It reacts with primary amines to form amide bonds, enabling stable attachment of payloads to biomolecules.
- Peg/alkyl/ether-based linker suitable for conjugation chemistry.
- Reactive NHS ester functional group for coupling to primary amines.
- Cleavable linker properties useful for ADC and PROTAC designs.
- Available in multiple pack sizes, including a 100 MG option.
- High purity, typically around 98.0%.
Medchemexpress LLC Biotin-C10-NHS ester | 887628-40-2 | MFCD05865045 | 99.5% | 524.67 | C25H40N4O6S | 5 MG
Biotin-C10-NHS ester is an alkyl/ether-based PROTAC linker bearing an N-hydroxysuccinimide (NHS) ester and a ten-carbon biotin spacer. It reacts with primary amines to install a biotin handle for affinity capture, target identification, and PROTAC probe construction. The compound is supplied as a solid with reported high purity and recommended low-temperature storage to maintain stability.
- Alkyl/ether-based PROTAC linker suited for probe design.
- NHS ester for efficient coupling to primary amines.
- Ten-carbon biotin spacer for robust affinity capture.
- Supplied as a solid with reported high purity.
- Storage conditions preserve stability (powder -20°C).
eMolecules Combi-Blocks Mal-PEG2-NHS ester 100mg 303339072 QI-6954 98 000 1433997-01-3 MFCD24539465 354 315 C15H18N2O8
Combi-Blocks Mal-PEG2-NHS ester 100mg 303339072 QI-6954 98 000 1433997-01-3 MFCD24539465 354 315 C15H18N2O8
Apexbio Technology LLC Sulfo-NHS-SS-11-Biotin 1g
Sulfo-NHS-SS-11-Biotin is an amine-reactive water-soluble biotinylation reagent containing an N-hydroxysulfosuccinimide (Sulfo-NHS) active ester group and a cleavable disulfide bond The Sulfo-NHS moiety reacts specifically with primary amines in proteins peptides or other biomolecules forming stable amide linkages This reagent introduces a disulfide-containing spacer arm enabling subsequent selective cleavage under reducing conditions for release of biotinylated molecules It is commonly employed in affinity chromatography immunoprecipitation experiments cell surface protein labeling and target identification allowing isolation purification or detection of biomolecules through streptavidin or avidin affinity interactions
Medchemexpress LLC Biotin-oxytocin (biotin-a-hypophamine; biotin-oxytocic hormone) | 99.3% | 1233.48 | C53H80N14O14S3 | 10 MG
Biotin-oxytocin is an N-terminally biotinylated form of the oxytocin peptide supplied for laboratory research use. The peptide retains the native disulfide-stabilized backbone while providing an N-terminal biotin tag for affinity capture, labeling, and detection in biochemical and cell-based assays. Supplied with supporting documentation including a datasheet and COA.
- 99.3% purity.
- Molecular weight 1233.48 Da.
- Sequence: biotin-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (disulfide Cys1-Cys6).
- Available sizes: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.
- Supplied with datasheet, COA, and SDS.
- Intended for research use only.
![Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203007.png-250.jpg)
Medchemexpress LLC 2,5-pyrrolidinedione, 1,1'-[1,2-ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]]bis- (9CI) | 65869-63-8 | 99.2% | 400.34 g/mol | C16H20N2O10 | 250 MG
Bis-PEG2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker bearing N-hydroxysuccinimide (NHS) ester reactive groups at both ends, designed for antibody-agent conjugation via amine-coupling chemistry for research use.
- Noncleavable two-unit PEG linker for antibody-agent conjugation.
- N-hydroxysuccinimide (NHS) ester reactive groups for amine coupling.
- High purity, 99.2%.
- Molecular weight 400.34 g/mol.
- Soluble in DMSO at 100 mg/mL; ultrasonic agitation may be required.
- Storage: powder at -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
- Available in multiple pack sizes, including 250 MG.
Apexbio Technology LLC Biotin-16-dUTP(Synonyms: Biotin-16-2'-deoxyuridine-5'-triphosphate, Biotin-16-dUTP nucleotide), 10ul (5 mM).
Biotin-16-dUTP is a biotin-labeled nucleotide analog utilized extensively in biomedical research for nucleic acid modification and detection Structurally modified to contain a biotin moiety linked via a 16-carbon spacer this compound functions by enzymatic incorporation into DNA strands mediated by DNA polymerases Following integration the biotin group serves as an affinity tag enabling subsequent detection through biotin-binding proteins such as streptavidin Applications include DNA labeling techniques in fluorescence microscopy and flow cytometry facilitating the visualization and analysis of nucleic acids in vitro
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | MFCD23381190 | ≥97.0% | 501.49 | C20H31N5O10 | 5 G
DOTA-NHS-ester is an N-hydroxysuccinimide ester derivative of the DOTA chelator used to conjugate amine-containing molecules for radiolabeling and imaging probe development. It is supplied as a solid and is handled and stored under low-temperature, moisture-free conditions.
- Used to conjugate DOTA to primary amines for PET and SPECT probe development.
- High purity suitable for research applications.
- Soluble in DMSO at 50 mg/mL; protocols provided for aqueous in vivo formulations.
- Stable as a solid when stored sealed at -20 °C; dissolved samples have recommended cold storage times.
- Molecular weight 501.49 and CAS number 170908-81-3 for unambiguous identification.
Apexbio Technology LLC Sulfo-NHS-LC-Biotin, 100mg. Cas: 127062-22-0 MFCD: MFCD00078534. Amine-reactive biotinylation reagent, long chain
Intermediate length, water-soluble biotinyltation reagent used to attach biotin to primary amines 127062-22-0. MFCD00078534
Medchemexpress LLC Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo... | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 g/mol | C56H80N12O9S | 50 MG
Ibrutinib-biotin is a biotin-conjugated chemical probe derived from the BTK inhibitor ibrutinib. It features ibrutinib linked to biotin via a long-chain linker and is designed for target engagement, affinity pull-downs, and assay development directed at Bruton's tyrosine kinase (BTK).
- Biotin-conjugated probe for affinity capture and pull-down assays.
- Derived from a BTK inhibitor for target-specific engagement.
- Low-nanomolar potency against BTK (IC50 0.755-1.02 nM).
- High purity suitable for research applications (>99.6%).
- Available as solid material and as a 10 mM solution in DMSO.
- Molecular weight approximately 1,097.37 g/mol.
Medchemexpress LLC CD79B Human Biotin 100ug
Recombinant human CD79B (extracellular residues Ala29-Asp159) produced in HEK293 cells and enzymatically biotinylated via an Avi tag. The construct includes a C-terminal His-Avi fusion, is >95% pure, and migrates ~35-45 kDa on SDS-PAGE due to glycosylation. Supplied with storage and reconstitution guidance for use in immobilization and binding assays.
- Site-specific biotinylation for consistent immobilization.
- C-terminal His-Avi tag for purification and controlled biotinylation.
- Mammalian expression preserves native glycosylation and folding.
- High purity suitable for ELISA, SPR/BLI, and flow cytometry.
- Storage and reconstitution recommendations to maintain activity.
Medchemexpress LLC N-(NHS ester-PEG2)-N-bis(PEG3-azide) | 99.9% | 704.73 | C28H48N8O13 | 10 MG
N-(NHS ester-PEG2)-N-bis(PEG3-azide) is a bifunctional polyethylene glycol (PEG) linker containing an N-hydroxysuccinimide (NHS) ester and two terminal azide groups. It is supplied as a high-purity reagent for bioconjugation and click chemistry applications, enabling amine-reactive coupling and subsequent azide-alkyne cycloaddition.
- Reactive N-hydroxysuccinimide (NHS) ester for conjugation to primary amines.
- Two terminal azide groups for copper-catalyzed or strain-promoted click chemistry.
- Compact PEG spacer improves solubility and reduces steric hindrance.
- High purity (99.90%) suitable for research applications.
- Typical appearance: liquid; molecular weight 704.73 Da; formula C28H48N8O13.
- Store sealed at -20°C, protected from moisture and light.
- Available in small mg-scale quantities for research use.